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Journal Articles

Localization estimation of ionizing radiation-induced abasic sites in DNA in the solid state using fluorescence resonance energy transfer

Akamatsu, Ken; Shikazono, Naoya; Saito, Takeshi*

Radiation Research, 183(1), p.105 - 113, 2015/01

 Times Cited Count:19 Percentile:64.18(Biology)

Clustered DNA damage is considered an important factor in determining the biological consequences of ionizing radiation. We here succeeded in estimating the localization of abasic sites (APs) in DNA irradiated with ionizing radiation using fluorescence resonance energy transfer (FRET) without any involvement of repair enzyme functions. A linearized plasmid was irradiated with $$^{60}$$Co $$gamma$$-rays, the $$^{4}$$He$$^{2+}$$ beam, and the $$^{12}$$C$$^{5+}$$ beam in the solid state. A donor or acceptor fluorescent probe with a nucleophilic O-amino group was used to label APs. The results showed that the $$^{12}$$C$$^{5+}$$ beam likely produced close APs within a track. On the other hand, E values of $$^{60}$$Co $$gamma$$-rays and the $$^{4}$$He$$^{2+}$$ beam were less than those of the $$^{12}$$C$$^{5+}$$ beam, increased with increasing AP density, and were slightly greater than those of randomly distributed APs.

JAEA Reports

Studies of neutronics calculation of high conversion light water reactor

; Okumura, Keisuke; Takano, Hideki;

JAERI-M 90-109, 49 Pages, 1990/07

JAERI-M-90-109.pdf:1.4MB

no abstracts in English

Journal Articles

Measurement of $$^{122}$$Sn neutron resonance parameters

Nakajima, Yutaka; Okubo, Makio; *; Mizumoto, Motoharu; Sugimoto, Masayoshi; Kawarasaki, Yuki

Annals of Nuclear Energy, 17(2), p.95 - 99, 1990/00

 Times Cited Count:1 Percentile:19.59(Nuclear Science & Technology)

no abstracts in English

Journal Articles

S-wave neutron strength function of Ta-181

*; ; *

Journal of Nuclear Science and Technology, 20(8), p.707 - 709, 1983/00

 Times Cited Count:1 Percentile:27.09(Nuclear Science & Technology)

no abstracts in English

Oral presentation

Localization estimation of radiation-induced DNA damage by FRET

Akamatsu, Ken; Shikazono, Naoya

no journal, , 

no abstracts in English

Oral presentation

Development of measurement method for an absolute value of resonance energy

Endo, Shunsuke; Kawamura, Shiori*; Tsuchikawa, Yusuke; Mishima, Kenji*; Kimura, Atsushi; Nakamura, Shoji; Iwamoto, Osamu; Iwamoto, Nobuyuki; Rovira Leveroni, G.

no journal, , 

no abstracts in English

7 (Records 1-7 displayed on this page)
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